Structure-activity relationships of synthetic tigogenyl glycosides

M Takechi; Y Tanaka

doi:10.1016/0031-9422(91)80008-o

Structure-activity relationships of synthetic tigogenyl glycosides

Phytochemistry. 1993 Nov;34(5):1241-3. doi: 10.1016/0031-9422(91)80008-o.

Authors

M Takechi¹, Y Tanaka

Affiliation

¹ Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka, Japan.

PMID: 7764282
DOI: 10.1016/0031-9422(91)80008-o

Abstract

Haemolytic activities of the five tigogenyl diglycosides and a maltotrioside were much stronger than those of nine monoglycosides. Among these glycosides, the glucoside, galactoside, maltoside, lactoside, gentiobioside, melibioside and maltotrioside had strong antifungal activity. By contrast, none of these glycosides showed any antibacterial activity.

Publication types

Comparative Study

MeSH terms

Anti-Infective Agents / chemistry
Anti-Infective Agents / pharmacology
Antifungal Agents / chemistry
Antifungal Agents / pharmacology
Carbohydrate Sequence
Glycosides / chemistry*
Glycosides / pharmacology
Hemolysin Proteins / chemistry
Hemolysin Proteins / pharmacology
Microbial Sensitivity Tests
Molecular Sequence Data
Spirostans / chemistry*
Structure-Activity Relationship

Substances

Anti-Infective Agents
Antifungal Agents
Glycosides
Hemolysin Proteins
Spirostans
sarsasapogenin