Abstract
A number of imidazo[2,1-b]thiazole guanylhydrazones, whose antitumor activity has already been described, were tested as potential cardiotonic agents. The guanylhydrazone of 2,3-dihydro-6-chloroimidazo[2,1-b]thiazole-5-carboxaldehyde (2a) was the most interesting compound showing both antitumor and cardiotonic activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / pharmacology*
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Cardiotonic Agents / pharmacology*
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Guinea Pigs
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Hydrazones / pharmacology
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Imidazoles / pharmacology
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In Vitro Techniques
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Molecular Structure
Substances
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Antineoplastic Agents
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Cardiotonic Agents
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Hydrazones
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Imidazoles