Gestational trophoblastic tumors of the uterus: MR imaging--pathologic correlation

Gynecol Oncol. 1995 Jun;57(3):340-50. doi: 10.1006/gyno.1995.1153.

Abstract

The purpose of this study is to evaluate the MR findings of gestational trophoblastic tumors (GTTs). Ten patients who confirmed the diagnosis (4 choriocarcinomas and 6 invasive moles) constituted the basis of our study. The MR findings from these patients were prospectively correlated with the histopathology of resected tumor specimens. MR findings of 4 patients with choriocarcinomas were well-defined, hemorrhagic masses with central necrosis. In contrast, 6 patients with invasive moles showed ill-defined, permeative masses with densely enhanced solid components and tiny cystic lesions. The trophoblastic proliferation, coagulation necrosis, and molar villi had varying signal intensities on T1- and T2-weighted images. Our results suggest that MR imaging is a promising tool for noninvasive morphologic analysis of GTTs.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Choriocarcinoma / diagnosis*
  • Choriocarcinoma / pathology*
  • Choriocarcinoma / surgery
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Hydatidiform Mole / diagnosis*
  • Hydatidiform Mole / pathology*
  • Hydatidiform Mole / surgery
  • Magnetic Resonance Imaging
  • Middle Aged
  • Pregnancy
  • Prospective Studies
  • Trophoblastic Neoplasms / diagnosis*
  • Trophoblastic Neoplasms / pathology*
  • Trophoblastic Neoplasms / surgery
  • Uterine Neoplasms / diagnosis*
  • Uterine Neoplasms / pathology*
  • Uterine Neoplasms / surgery