Genetic and physical mapping of five novel microsatellite markers on human Xp21.1-p11.22

Genomics. 1995 Jan 1;25(1):279-81. doi: 10.1016/0888-7543(95)80136-a.

Abstract

Five polymorphic CA-dinucleotide repeats, identified in cosmids from the short arm of the human X chromosome, have been characterized and localized to Xp21.1 (DXS572), Xp11.4 (DXS556, DXS574), and Xp11.22-p11.23 (DXS722, DXS573). Genetic mapping with respect to five reference markers that include the gene for CGD (CYBB in Xp21.1), complemented by physical mapping information, has indicated the order tel-DXS572-CYBB-DXS1110-DXS556-DXS574-D XS7-DXS426-DXS722-DXS573-DXS255-cen.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Chromosome Deletion
  • Chromosome Mapping
  • DNA Primers
  • DNA, Satellite / genetics*
  • Genetic Carrier Screening
  • Genetic Markers
  • Hominidae / genetics*
  • Humans
  • Hybrid Cells
  • Meiosis
  • Mice
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Recombination, Genetic
  • Repetitive Sequences, Nucleic Acid*
  • X Chromosome*

Substances

  • DNA Primers
  • DNA, Satellite
  • Genetic Markers