Design and syntheses of potent and selective dipeptide inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase

J Med Chem. 1995 May 26;38(11):1837-40. doi: 10.1021/jm00011a001.
No abstract available

MeSH terms

  • Acyltransferases / antagonists & inhibitors*
  • Acyltransferases / metabolism
  • Amino Acid Sequence
  • Binding Sites
  • Candida albicans / enzymology*
  • Dipeptides / chemical synthesis*
  • Dipeptides / metabolism
  • Dipeptides / pharmacology*
  • Drug Design
  • Fungal Proteins / antagonists & inhibitors*
  • Kinetics
  • Molecular Sequence Data
  • Oligopeptides / chemical synthesis
  • Oligopeptides / metabolism
  • Oligopeptides / pharmacology
  • Structure-Activity Relationship
  • Substrate Specificity

Substances

  • Dipeptides
  • Fungal Proteins
  • Oligopeptides
  • Acyltransferases
  • glycylpeptide N-tetradecanoyltransferase