P-glycoprotein-mediated multidrug resistance in tumor cells: biochemistry, clinical relevance and modulation

Mol Aspects Med. 1995;16(1):1-78. doi: 10.1016/0098-2997(94)00040-a.
No abstract available

Publication types

  • Review

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / chemistry
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism*
  • Adenosine Triphosphatases / metabolism
  • Amino Acid Sequence
  • Animals
  • Antineoplastic Agents / metabolism
  • Antineoplastic Agents / therapeutic use*
  • Drug Resistance, Multiple* / genetics
  • Humans
  • Leukemia / drug therapy
  • Leukemia / genetics
  • Liver / metabolism
  • Lymphoma / drug therapy
  • Lymphoma / genetics
  • Molecular Sequence Data
  • Multiple Myeloma / drug therapy
  • Multiple Myeloma / genetics
  • Neoplasms / drug therapy*
  • Neoplasms / genetics*
  • Pharmaceutical Preparations / metabolism

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Antineoplastic Agents
  • Pharmaceutical Preparations
  • Adenosine Triphosphatases