Tumor suppressor gene alterations in bladder carcinoma. Translational correlates to clinical practice

G Dalbagni; C Cordon-Cardo; V Reuter; W R Fair

Tumor suppressor gene alterations in bladder carcinoma. Translational correlates to clinical practice

Surg Oncol Clin N Am. 1995 Apr;4(2):231-40.

Authors

G Dalbagni¹, C Cordon-Cardo, V Reuter, W R Fair

Affiliation

¹ Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

PMID: 7796283

Abstract

The most common tumor suppressor genes involved in the prediction of bladder tumor progression are the Rb and the p53 genes. This article summarizes current data on the use of these markers in prognostic evaluation.

Publication types

Review

MeSH terms

Carcinoma / genetics*
Carcinoma / pathology*
Gene Expression Regulation, Neoplastic
Genes, Retinoblastoma / genetics
Genes, Tumor Suppressor / genetics*
Genes, p53 / genetics
Genetic Markers / genetics
Humans
Prognosis
Urinary Bladder Neoplasms / genetics*
Urinary Bladder Neoplasms / pathology*

Substances

Genetic Markers