[Evaluation of the action of glucomannan on metabolic parameters and on the sensation of satiation in overweight and obese patients]

Clin Ter. 1995 Apr;146(4):269-74.
[Article in Italian]

Abstract

The authors studied the behavior of body weight, blood glucose, total serum cholesterol, and hunger and satiety sensation in 30 patients treated for 60 days with a 1.200 kcal (5040 kj) diet plus either placebo or glucomannane. All the variables considered show that the low-calorie diet plus glucomannane is more effective than the low-calorie diet alone.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Body Mass Index
  • Body Weight / drug effects
  • Cathartics / administration & dosage
  • Diet, Reducing
  • Dietary Fiber / administration & dosage
  • Double-Blind Method
  • Female
  • Gastrointestinal Transit / drug effects
  • Humans
  • Mannans / administration & dosage*
  • Mannans / pharmacology
  • Obesity / drug therapy*
  • Obesity / metabolism
  • Obesity, Morbid / drug therapy
  • Obesity, Morbid / metabolism
  • Satiation / drug effects*

Substances

  • Cathartics
  • Dietary Fiber
  • Mannans
  • (1-6)-alpha-glucomannan