Childhood sarcoidosis presenting with hypercalcaemic crisis

Sarcoidosis. 1994 Sep;11(2):141-3.

Abstract

We report a case of hypercalcaemic crisis due to sarcoidosis in a 15-year-old boy. The clinical suspicion of sarcoidosis was confirmed by a liver biopsy. At admission serum calcium, 1,25(OH)2 and ACE were elevated and iPTH was suppressed. The levels of serum total and ionized calcium, iPTH, ACE, 1,25(OH)2 and 25-OH were followed and chest X-ray and pulmonary function tests were performed during systemic steroid treatment. The clinical condition improved during treatment and the paraclinical measurements normalised within 5 weeks. The mechanism whereby hypercalcaemia occurs in childhood sarcoidosis is clarified.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Denmark / epidemiology
  • Humans
  • Hypercalcemia / etiology*
  • Incidence
  • Male
  • Prednisone / therapeutic use
  • Sarcoidosis / complications*
  • Sarcoidosis / drug therapy
  • Sarcoidosis / epidemiology

Substances

  • Prednisone