Corticotropin-releasing hormone enables weaning from ventilator in a neurosurgical patient under long-term controlled mechanical respiratory support

Zentralbl Neurochir. 1994;55(3):162-5.

Abstract

A patient with recurrent hemorrhage into the posterior fossa leading to loss of central respiratory drive is described. Repeated i.v. application of corticotropin-releasing hormone over a period of 24 days enabled weaning from long-term controlled mechanical ventilation by reinstitution and maintenance of spontaneous respiration.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / surgery*
  • Corticotropin-Releasing Hormone / administration & dosage*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Humans
  • Infusions, Intravenous
  • Intracranial Arteriovenous Malformations / diagnosis
  • Intracranial Arteriovenous Malformations / surgery*
  • Male
  • Neurologic Examination
  • Postoperative Complications / drug therapy*
  • Recurrence
  • Reoperation
  • Respiratory Paralysis / drug therapy*
  • Ventilator Weaning*

Substances

  • Corticotropin-Releasing Hormone