Involuntary movement disorders associated with felbamate

Neurology. 1995 Jan;45(1):185-7. doi: 10.1212/wnl.45.1.185.

Abstract

Two children developed involuntary movements while taking felbamate as an adjunct to their antiepileptic regimen. One exhibited choreoathetosis and the other an acute dystonic reaction. In both children the symptoms resolved with no recurrence after felbamate discontinuance.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Age of Onset
  • Akathisia, Drug-Induced / physiopathology*
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / blood
  • Anticonvulsants / therapeutic use
  • Electroencephalography
  • Felbamate
  • Humans
  • Infant
  • Male
  • Phenylcarbamates
  • Propylene Glycols / adverse effects*
  • Propylene Glycols / blood
  • Propylene Glycols / pharmacokinetics
  • Seizures / drug therapy*
  • Seizures / physiopathology

Substances

  • Anticonvulsants
  • Phenylcarbamates
  • Propylene Glycols
  • Felbamate