Abstract
Thirty-six patients with rheumatoid arthritis were studied to determine the effectiveness and safety of combined therapy with naproxen and aspirin. An 8-week double-blind crossover trial was performed in which naproxen and placebo were administered on a background of constant-dose aspirin. Combination therapy was demonstrated to be more effective than aspirin alone. Tolerance of the two regimens was comparable.
Publication types
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Case Reports
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Clinical Trial
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Controlled Clinical Trial
MeSH terms
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Adult
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Arthritis, Rheumatoid / drug therapy*
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Aspirin / adverse effects
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Aspirin / therapeutic use*
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Clinical Trials as Topic
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Drug Therapy, Combination
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Female
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Humans
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Male
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Middle Aged
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Naphthaleneacetic Acids / therapeutic use*
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Naproxen / adverse effects
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Naproxen / therapeutic use*
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Placebos
Substances
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Naphthaleneacetic Acids
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Placebos
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Naproxen
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Aspirin