Abstract
Cholecystokinin of the central nervous system participates in the pathogenesis of lipopolysaccharide-induced fever in rats, contributing mainly to the first phase rise of this fever. The mediatory role is connected to type-B receptors of cholecystokinin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Body Temperature Regulation / drug effects*
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Cholecystokinin / pharmacology*
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Female
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Fever / chemically induced
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Fever / metabolism
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Fever / physiopathology*
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Lipopolysaccharides
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Prostaglandins E / metabolism
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Rats
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Rats, Wistar
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Receptors, Cholecystokinin / metabolism
Substances
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Lipopolysaccharides
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Prostaglandins E
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Receptors, Cholecystokinin
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Cholecystokinin