Nephrotic syndrome and acute renal failure associated with hepatitis A virus infection

Am J Gastroenterol. 1995 Feb;90(2):295-8.

Abstract

Acute renal failure has been documented in association with hepatitis A virus (HAV) infection. This report describes a temporal relationship between HAV infection and immune complex mesangial proliferative glomerulonephritis associated with nephrotic syndrome. Animal experimental data have already shown that this is indeed a histological lesion associated with HAV infection. This case report is the first English documentation associating HAV infection with immune complex mesangial proliferative glomerulonephritis.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / immunology*
  • Acute Kidney Injury / virology
  • Adult
  • Antigen-Antibody Complex / analysis*
  • Fluorescent Antibody Technique
  • Glomerular Mesangium / immunology*
  • Glomerulonephritis, Membranoproliferative / immunology*
  • Glomerulonephritis, Membranoproliferative / virology
  • Hepatitis A / complications*
  • Hepatitis A / immunology
  • Humans
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Male
  • Microscopy, Electron
  • Nephrotic Syndrome / immunology*
  • Nephrotic Syndrome / virology

Substances

  • Antigen-Antibody Complex
  • Immunoglobulin G
  • Immunoglobulin M