Impaired healing of cervical oesophagogastrostomies can be predicted by estimation of gastric serosal blood perfusion by laser Doppler flowmetry

Eur J Surg. 1994 Nov;160(11):599-603.

Abstract

Objective: To assess the value of relative blood perfusion of the gastric tube in prediction of impaired healing of cervical oesophagogastrostomies.

Design: Prospective study.

Setting: University hospital, The Netherlands.

Subjects: Thirty patients undergoing transhiatal oesophagectomy and partial gastrectomy for cancer of the oesophagus or oesophagogastric junction, with gastric tube reconstruction and cervical oesophagogastrostomy.

Main outcome measures: Operative measurement of gastric blood perfusion at four sites by laser Doppler flowmetry and perfusion of the same sites after construction of the gastric tube expressed as a percentage of preconstruction values.

Results: The relative perfusion at the most proximal site of the gastric tube was significantly lower than at the more distal sites (p = 0.001). Nine of 18 patients (50%) in whom the perfusion of the proximal gastric tube was less than 70% of preconstruction values developed an anastomotic stricture, compared with only 1 of 12 patients (8%) with a relative perfusion of 70% or more (p = 0.024). A reduction in perfusion of the gastric tube did not predict leakage.

Conclusion: Impaired anastomotic healing is unlikely if relative perfusion is 70% or more of preconstruction values. Perfusion of less than 70% partly predicts the occurrence of anastomotic stricture, but leakage cannot be predicted. Factors other than blood perfusion may have a role in the process of anastomotic healing.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Anastomosis, Surgical / adverse effects
  • Anastomosis, Surgical / methods*
  • Constriction, Pathologic / etiology
  • Esophageal Neoplasms / surgery
  • Esophagectomy
  • Esophagostomy / adverse effects
  • Esophagus / surgery*
  • Female
  • Forecasting
  • Gastrectomy
  • Gastric Mucosa / blood supply*
  • Gastrostomy / adverse effects
  • Humans
  • Laser-Doppler Flowmetry*
  • Male
  • Middle Aged
  • Prospective Studies
  • Regional Blood Flow / physiology
  • Stomach / blood supply
  • Stomach / surgery*
  • Stomach Neoplasms / surgery
  • Wound Healing