A study of the frontozygomatic region (FZ) to determine an anatomic basis for the use of miniplates in this area was done. Plaster models were obtained from 35 adult skulls and were sectioned at six defined points. Osseous thickness measurements were made perpendicularly to the bone surface. Measurements to determine the risk of penetrating the cranial cavity were also done. The results show that above the FZ suture 5-mm screws should be used. At the two points below the suture, 7-mm screws can be used. The risk of penetrating to the cranial cavity occurs 10 mm above the suture. The diploe thickness at the level of the anterior cranial fossa floor indicates the use of a 7-mm screw at a distance 13.5-18.5 mm from the suture and 5-mm screws above 18.5 mm.