Reduction of RI alpha subunit of cAMP-dependent protein kinase expression induces growth inhibition of human mammary epithelial cells transformed by TGF-alpha, c-Ha-ras, and c-erbB-2 genes

Ann N Y Acad Sci. 1993 Nov 30:698:102-7. doi: 10.1111/j.1749-6632.1993.tb17194.x.

Authors

F Ciardiello¹, G Tortora, S Pepe, C Bianco, G Baldassarre, A Ruggiero, C Bianco, M P Selvam, A R Bianco

Affiliation

¹ Cattedra di Oncologia Medica, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli, Italy.

PMID: 7904135
DOI: 10.1111/j.1749-6632.1993.tb17194.x

No abstract available

MeSH terms

8-Bromo Cyclic Adenosine Monophosphate / analogs & derivatives
8-Bromo Cyclic Adenosine Monophosphate / pharmacology
Base Sequence
Breast / cytology*
Cell Division / drug effects
Cell Line, Transformed
Cell Transformation, Neoplastic*
Cyclic AMP-Dependent Protein Kinases / biosynthesis*
Epithelial Cells
Epithelium / enzymology
Epithelium / pathology
ErbB Receptors / genetics*
Female
Genes, ras*
Humans
Macromolecular Substances
Molecular Sequence Data
Oligonucleotides, Antisense / pharmacology*
Proto-Oncogene Proteins / genetics*
Proto-Oncogene Proteins p21(ras) / biosynthesis
Proto-Oncogenes*
Receptor, ErbB-2
Transforming Growth Factor alpha / biosynthesis*

Substances

Macromolecular Substances
Oligonucleotides, Antisense
Proto-Oncogene Proteins
Transforming Growth Factor alpha
8-Bromo Cyclic Adenosine Monophosphate
8-chloro-cyclic adenosine monophosphate
ErbB Receptors
Receptor, ErbB-2
Cyclic AMP-Dependent Protein Kinases
HRAS protein, human
Proto-Oncogene Proteins p21(ras)