Bovine histidine-rich glycoprotein is a substrate for bovine plasma factor XIIIa

T Halkier; H Andersen; A Vestergaard; S Magnusson

doi:10.1006/bbrc.1994.1416

Bovine histidine-rich glycoprotein is a substrate for bovine plasma factor XIIIa

Biochem Biophys Res Commun. 1994 Apr 15;200(1):78-82. doi: 10.1006/bbrc.1994.1416.

Authors

T Halkier¹, H Andersen, A Vestergaard, S Magnusson

Affiliation

¹ Department of Molecular Biology and Plant Physiology, University of Aarhus, Denmark.

PMID: 7909439
DOI: 10.1006/bbrc.1994.1416

Abstract

Histidine-rich glycoprotein was purified from bovine plasma and the identity of the protein confirmed through amino acid sequencing. Activated bovine factor XIIIa catalyzed the incorporation of 1 nmol of 1,4-[14C]putrescine into 1 nmol of bovine histidine-rich glycoprotein, showing that histidine-rich glycoprotein has the ability to participate in transglutaminase-catalyzed reactions in vivo.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Blood Proteins / isolation & purification
Blood Proteins / metabolism*
Carbon Radioisotopes
Cattle
Glycoproteins / metabolism*
Histidine-Rich Glycoprotein
Humans
Kinetics
Molecular Sequence Data
Proteins / isolation & purification
Proteins / metabolism*
Putrescine / metabolism
Substrate Specificity
Transglutaminases / isolation & purification
Transglutaminases / metabolism*

Substances

Blood Proteins
Carbon Radioisotopes
Glycoproteins
Proteins
Histidine-Rich Glycoprotein
Transglutaminases
Putrescine