Diagnostic localization studies for primary hyperparathyroidism. A suggested algorithm

Arch Otolaryngol Head Neck Surg. 1994 Nov;120(11):1187-9. doi: 10.1001/archotol.1994.01880350005001.

Abstract

Objective: To assess the accuracy of preoperative imaging studies in primary hyperparathyroidism.

Design: Retrospective review of all patients treated surgically for primary hyperparathyroidism at The University of California-San Diego Medical Center between January 1990 and May 1992. Results of preoperative imaging studies were compared with surgical and pathologic findings.

Setting: The University of California-San Diego Medical Center, a primary care and referral center.

Participants: Twenty-eight patients were included in the study, and a total of 41 imaging studies were obtained.

Outcome measures: The accuracy of preoperative imaging studies in correctly localizing the site of a parathyroid adenoma.

Results: Ultrasound correctly identified the site of a solitary parathyroid adenoma in 82% of cases, and magnetic resonance imaging in 80% of cases. The adenomas that were not localized by ultrasound were correctly localized by magnetic resonance imaging. These findings are discussed within the context of recent trends in parathyroid surgery.

Conclusions: Based on the results and a review of the literature, a simple algorithm for the use of these imaging studies is proposed. Use of this algorithm will improve preoperative planning, and potentially reduce operative time and morbidity.

MeSH terms

  • Adenoma / complications
  • Adenoma / diagnosis*
  • Adenoma / diagnostic imaging
  • Algorithms
  • Humans
  • Hyperparathyroidism / etiology*
  • Magnetic Resonance Imaging
  • Parathyroid Neoplasms / complications
  • Parathyroid Neoplasms / diagnosis*
  • Parathyroid Neoplasms / diagnostic imaging
  • Predictive Value of Tests
  • Retrospective Studies
  • Ultrasonography