t(8;13) (p11;q12) translocation in a myeloproliferative disorder associated with a T-cell non-Hodgkin lymphoma

J Leslie; T Barker; M Glancy; B Jennings; J Pearson

doi:10.1111/j.1365-2141.1994.tb04847.x

t(8;13) (p11;q12) translocation in a myeloproliferative disorder associated with a T-cell non-Hodgkin lymphoma

Br J Haematol. 1994 Apr;86(4):876-8. doi: 10.1111/j.1365-2141.1994.tb04847.x.

Authors

J Leslie¹, T Barker, M Glancy, B Jennings, J Pearson

Affiliation

¹ Department of Haematology, Norfolk and Norwich Hospital.

PMID: 7918088
DOI: 10.1111/j.1365-2141.1994.tb04847.x

Abstract

An unusual cytogenetic translocation, t(8;13) (p11;q12), is described in a patient presenting with a CML-like myeloproliferative disorder associated with a high-grade T-cell lymphoma. Evidence is presented suggesting that the breakpoint region in the translocation involves a site implicated in both the T cell malignancy and the abnormal granulocyte proliferation.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Chromosomes, Human, Pair 13*
Chromosomes, Human, Pair 8*
Humans
Karyotyping
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / genetics*
Lymphoma, T-Cell / genetics*
Lymphoma, T-Cell / pathology
Male
Neoplasms, Multiple Primary / genetics
Translocation, Genetic*