A water-soluble 1,2-diaminocyclohexaneplatinum(II) complex containing procaine hydrochloride: synthesis and antiproliferative activity in vitro

Pharmazie. 1994 Aug;49(8):617-8.

Authors

S Cafaggi¹, M Esposito, B Parodi, M Viale

Affiliation

¹ Istituto di Analisi e Tecnologie Farmaceutiche ed Alimentari dell'Università di Genova, Italy.

PMID: 7938154

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents / chemical synthesis*
Antineoplastic Agents / pharmacology
Blood Urea Nitrogen
DNA, Neoplasm / biosynthesis
Female
Leukemia P388 / drug therapy
Leukemia P388 / metabolism
Mice
Mice, Inbred Strains
Organoplatinum Compounds / chemical synthesis*
Organoplatinum Compounds / pharmacology
Procaine / analogs & derivatives*
Procaine / chemical synthesis
Procaine / pharmacology
Thymidine / metabolism
Tumor Cells, Cultured

Substances

Antineoplastic Agents
DNA, Neoplasm
Organoplatinum Compounds
procaine-chloro-1,2-diaminocyclohexaneplatinum(II)
Procaine
Thymidine