Successful bone marrow transplant for Fanconi anaemia in transformation

Bone Marrow Transplant. 1994 Jul;14(1):151-3.

Abstract

We present a patient who was diagnosed as suffering from Fanconi anaemia at the age of 36 years. At the time of diagnosis his bone marrow showed features of pre-leukaemic transformation. He received an allogeneic bone marrow transplant (BMT) from his HLA-identical sibling. The post-transplant course was unremarkable with evidence of trilineage engraftment at day +32 and no acute or chronic GVHD. He is well with sustained engraftment and no haematological evidence of Fanconi anaemia 18 months post-transplant.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Marrow Transplantation*
  • Chimera / genetics
  • DNA, Satellite / genetics
  • Fanconi Anemia / genetics
  • Fanconi Anemia / therapy*
  • Graft vs Host Disease / prevention & control
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Preleukemia / genetics
  • Preleukemia / therapy*
  • Transplantation, Homologous

Substances

  • DNA, Satellite