Receptor-mediated toxicity and implications for risk assessment

Prog Clin Biol Res. 1994:387:295-310.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Division / drug effects
  • Cocarcinogenesis
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 Enzyme System / metabolism
  • Diethylnitrosamine / toxicity
  • Dose-Response Relationship, Drug
  • Enzyme Induction / drug effects
  • Female
  • Gene Expression Regulation / drug effects
  • Growth Substances / physiology
  • Humans
  • Liver Neoplasms, Experimental / chemically induced
  • Models, Biological*
  • Oxidoreductases / metabolism
  • Phenobarbital / toxicity
  • Polychlorinated Dibenzodioxins / adverse effects
  • Polychlorinated Dibenzodioxins / pharmacokinetics
  • Polychlorinated Dibenzodioxins / toxicity*
  • Rats
  • Receptors, Aryl Hydrocarbon / drug effects*
  • Receptors, Aryl Hydrocarbon / physiology
  • Risk Assessment

Substances

  • Growth Substances
  • Polychlorinated Dibenzodioxins
  • Receptors, Aryl Hydrocarbon
  • Diethylnitrosamine
  • Cytochrome P-450 Enzyme System
  • Oxidoreductases
  • Cytochrome P-450 CYP1A2
  • Phenobarbital