A sodium magnetic resonance imaging study of acute cerebral ischaemia in the gerbil

Acta Neurochir Suppl (Wien). 1994:60:220-3. doi: 10.1007/978-3-7091-9334-1_59.

Abstract

23Na magnetic resonance imaging has been used to investigate sodium changes during and after cerebral ischaemia in a gerbil model. The sodium signal decreased within 4 minutes of the onset of ischaemia, and subsequently increased between 4 and 8 minutes after the onset of reperfusion. These observations may be reflecting the redistribution of tissue sodium resulting from energy failure and recovery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood-Brain Barrier / physiology*
  • Brain / blood supply
  • Brain / pathology
  • Brain Edema / physiopathology*
  • Brain Ischemia / physiopathology*
  • Brain Mapping
  • Cerebral Infarction / physiopathology
  • Energy Metabolism / physiology
  • Gerbillinae
  • Magnetic Resonance Imaging / methods*
  • Male
  • Sodium / metabolism*
  • Water-Electrolyte Balance / physiology*

Substances

  • Sodium