Comparative effectiveness of hand-cleansing agents for removing methicillin-resistant Staphylococcus aureus from experimentally contaminated fingertips

Am J Infect Control. 1994 Aug;22(4):224-7. doi: 10.1016/0196-6553(94)99000-x.

Abstract

Background: Five subjects participated in a study of optimal conditions for removing methicillin-resistant Staphylococcus aureus from contaminated fingertips.

Methods: Fingertips were contaminated experimentally and cleaned by various methods. Bacterial removal was measured as percentage and is given as mean +/- standard error of the mean.

Results: Rinsing the fingertips with tap water for 20 seconds and drying them with paper towels removed 95.2% +/- 1.6% of the contamination. Application of hand-cleansing agents to fingertips for 20 seconds, followed by a 20-second tap-water rinse and towel drying, removed bacteria as follows: povidone-iodine detergent, 99.2% +/- 0.4%; chlorhexidine detergent, 97.2% +/- 0.8%; and liquid soap, 96.1% +/- 1.1%. In a modification of the method, 80% ethyl alcohol applied to the fingertips for 20 seconds, followed by air drying for 40 seconds, removed 99.1% +/- 0.8% of the bacteria. Statistical analyses indicated that povidone-iodine and 80% ethyl alcohol were more effective than the other agents.

Conclusions: Rinsing contaminated fingertips with tap water and towel drying them is sufficient to reduce contamination with methicillin-resistant S. aureus by 95%. Washing with povidone-iodine or 80% ethyl alcohol further reduces contamination by an additional 99%.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Anti-Infective Agents, Local / pharmacology*
  • Chlorhexidine / pharmacology
  • Ethanol / pharmacology
  • Evaluation Studies as Topic
  • Female
  • Fingers / microbiology*
  • Hand Disinfection / methods*
  • Humans
  • Male
  • Methicillin Resistance
  • Povidone-Iodine / pharmacology
  • Soaps / pharmacology
  • Staphylococcus aureus / isolation & purification*

Substances

  • Anti-Infective Agents, Local
  • Soaps
  • Ethanol
  • Povidone-Iodine
  • Chlorhexidine