Abstract
Melanized Cryptococcus neoformans cells were less susceptible than nonmelanized cells to the fungicidal effects of UV light. Phenoloxidase-catalyzed production of melanin-like pigments may serve to protect the fungus against ionizing radiation.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cryptococcosis / etiology
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Cryptococcus neoformans / metabolism
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Cryptococcus neoformans / pathogenicity
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Cryptococcus neoformans / radiation effects*
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Humans
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Melanins / metabolism*
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Meningoencephalitis / etiology
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Ultraviolet Rays