MRI and CT in Krabbe's disease: case report

Neuroradiology. 1994 Aug;36(6):477-9. doi: 10.1007/BF00593688.

Abstract

A case of infantile Krabbe's disease was first recognised as areas of relatively increased density on CT in the thalamus lateral geniculate body and dentate nucleus. These sites were subsequently shown on MRI to have a paramagnetic effect, being characterised by short T2 and T1. Subsequent examinations showed development of atrophy and high signal in white matter.

Publication types

  • Case Reports

MeSH terms

  • Atrophy
  • Brain / pathology*
  • Brain Diseases, Metabolic / diagnosis*
  • Brain Diseases, Metabolic / genetics
  • Cerebellar Nuclei / pathology
  • Geniculate Bodies / pathology
  • Humans
  • Infant
  • Leukodystrophy, Globoid Cell / diagnosis*
  • Leukodystrophy, Globoid Cell / genetics
  • Magnetic Resonance Imaging*
  • Male
  • Neurologic Examination
  • Thalamus / pathology
  • Tomography, X-Ray Computed*