[Effects of seeds, leaves and fruits of Ziziphus spinosa and jujuboside A on central nervous system function]

Zhongguo Zhong Yao Za Zhi. 1993 Nov;18(11):685-7, 703-4.
[Article in Chinese]

Abstract

The seeds and leaves of Ziziphus Spinosa exert a similar inhibiting effect on central nervous system function, while the fruits have a synergism with pentobarbitol sodium and thiopental sodium on prolongation of sleep and sedation, also decreases coordinated action. Jujuboside A exerts no inhibiting effect, but a synergism with phenylalanine on central nervous system function.

MeSH terms

  • Animals
  • Drug Synergism
  • Drugs, Chinese Herbal / pharmacology*
  • Female
  • Hypnotics and Sedatives / pharmacology*
  • Male
  • Mice
  • Motor Activity / drug effects*
  • Pentobarbital / pharmacology
  • Phenylalanine / pharmacology
  • Rats
  • Rats, Wistar
  • Saponins / pharmacology
  • Sleep / drug effects*
  • Thiopental / pharmacology

Substances

  • Drugs, Chinese Herbal
  • Hypnotics and Sedatives
  • Saponins
  • Phenylalanine
  • jujuboside A
  • Pentobarbital
  • Thiopental