Autosomal recessive polycystic kidney disease does not map to the second gene locus for autosomal dominant polycystic kidney disease on chromosome 4

K Zerres; G Mücher; S Rudnik-Schöneborn

doi:10.1007/BF00201574

Autosomal recessive polycystic kidney disease does not map to the second gene locus for autosomal dominant polycystic kidney disease on chromosome 4

Hum Genet. 1994 Jun;93(6):697-8. doi: 10.1007/BF00201574.

Authors

K Zerres¹, G Mücher, S Rudnik-Schöneborn

Affiliation

¹ Institut für Humangenetik, Universität Bonn, Germany.

PMID: 8005596
DOI: 10.1007/BF00201574

Abstract

Linkage analysis in 19 families with autosomal recessive polycystic kidney disease (ARPKD) has shown that ARPKD is not linked to the recently assigned second gene locus for autosomal dominant polycystic kidney disease (ADPKD) on chromosome 4q (PKD2). Thus, there is strong evidence that ADPKD and ARPKD have different gene loci.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosome Mapping
Chromosomes, Human, Pair 4*
Genetic Linkage
Genetic Markers
Humans
Polycystic Kidney, Autosomal Dominant / genetics*
Polycystic Kidney, Autosomal Recessive / genetics*

Substances

Genetic Markers