[Interferon and blood tumor necrosis factor in 95 patients with HIV infection]

J Constans; J L Pellegrin; I Pellegrin; E Peuchant; M F Dumon; C Sergeant; M Simonoff; G Brossard; P Barbeau; M Clerc

doi:10.1016/s0248-8663(05)80122-5

[Interferon and blood tumor necrosis factor in 95 patients with HIV infection]

Rev Med Interne. 1993;14(10):1004. doi: 10.1016/s0248-8663(05)80122-5.

[Article in French]

Authors

J Constans¹, J L Pellegrin, I Pellegrin, E Peuchant, M F Dumon, C Sergeant, M Simonoff, G Brossard, P Barbeau, M Clerc, et al.

Affiliation

¹ Service de médecine interne et pathologie vasculaire, hôpital Saint-André, Bordeaux.

PMID: 8009002
DOI: 10.1016/s0248-8663(05)80122-5

Abstract

We have measured TNF-alpha and interferon alpha in 95 HIV positive patients and 20 healthy subjects. TNF-alpha was higher in the HIV+ patients (P = 0.0001) and was correlated to the CD4 cell count (P = 0.02) and cholesterol (negatively) (P = 0.04). Interferon-alpha was correlated to the wasting syndrome (P = 0.002), hypertriglyceridemia (P = 0.004) and haematocrit (P = 0.04).

Publication types

English Abstract

MeSH terms

HIV Seropositivity / blood*
Humans
Interferon-alpha / blood*
Lipid Metabolism
Tumor Necrosis Factor-alpha / analysis*

Substances

Interferon-alpha
Tumor Necrosis Factor-alpha