Surface coil cardiac tagging and 31P spectroscopic localization with B1-insensitive adiabatic pulses

Magn Reson Med. 1994 May;31(5):541-5. doi: 10.1002/mrm.1910310511.

Abstract

A technique is presented for MRI tagging in the presence of inhomogeneous B1 fields. A rectangular tagging grid is produced with B1-insensitive adiabatic pulses in a magnetization preparation period that precedes image acquisition. Phantom results demonstrate that the method is well-suited to surface coil experiments. The technique is applied to a canine model of myocardial ischemia to track the spatially dependent wall motion of the left ventricle during the cardiac cycle. Transmural 31P spectra are acquired from the same double-tuned surface coil, with tagging and spectroscopy performed for the first time, during normal, ischemic, and recovery conditions for the same animal.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Animals
  • Coronary Vessels / physiology
  • Diastole / physiology
  • Dogs
  • Fourier Analysis
  • Image Enhancement / methods*
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Spectroscopy* / methods
  • Magnetics
  • Models, Cardiovascular
  • Models, Structural
  • Myocardial Ischemia / metabolism*
  • Myocardial Reperfusion*
  • Myocardium / metabolism*
  • Phosphates / metabolism
  • Phosphocreatine / metabolism
  • Phosphorus
  • Systole / physiology
  • Ventricular Function, Left / physiology

Substances

  • Phosphates
  • Phosphocreatine
  • Phosphorus
  • Adenosine Triphosphate