Giant-cell fibroblastoma with pigmented dermatofibrosarcoma protuberans component

Am J Surg Pathol. 1994 Jul;18(7):736-40. doi: 10.1097/00000478-199407000-00010.

Abstract

A unique case of giant-cell fibroblastoma that contained a pigmented dermatofibrosarcoma component (Bednár tumor) is described. The melanin pigmented dendritic cells found in the dermatofibrosarcoma component were round or spindle-shaped and had bipolar extensions. They were S-100 protein positive. Our case indicates the close histogenetic relationship between giant-cell fibroblastoma and dermatofibrosarcoma protuberans. The occurrence of the pigmented melanin-laden dendritic cells in our tumor further substantiates the theory that Bednár tumor is a pigmented variant of dermatofibrosarcoma protuberans.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dermatofibrosarcoma / metabolism
  • Dermatofibrosarcoma / pathology*
  • Fibroma / metabolism
  • Fibroma / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Shoulder*
  • Soft Tissue Neoplasms / metabolism
  • Soft Tissue Neoplasms / pathology*
  • Vimentin / metabolism

Substances

  • Vimentin