Abstract
The relationship between levels of urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) and symptom scores on the Hamilton Rating Scale for Depression was examined in 31 patients with unipolar depression. Patients with either low MHPG or high MHPG showed significant sleep disturbance in the form of early morning awakening. Patients with mid-range or high MHPG showed decreased work and activities. Endogenomorphy factor scores represented a blend of these findings.
Publication types
-
Comparative Study
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adult
-
Body Weight
-
Cognition Disorders / complications
-
Cognition Disorders / diagnosis
-
Cognition Disorders / urine
-
Depressive Disorder / complications
-
Depressive Disorder / diagnosis*
-
Depressive Disorder / urine
-
Dexamethasone
-
Female
-
Humans
-
Hydrocortisone / blood
-
Male
-
Methoxyhydroxyphenylglycol / urine*
-
Middle Aged
-
Psychiatric Status Rating Scales
-
Psychomotor Disorders / complications
-
Psychomotor Disorders / diagnosis
-
Psychomotor Disorders / urine
-
Sleep Wake Disorders / complications
-
Sleep Wake Disorders / diagnosis
-
Sleep Wake Disorders / urine
-
Thyrotropin / blood
-
Thyroxine / blood
-
Triiodothyronine / blood
Substances
-
Triiodothyronine
-
Methoxyhydroxyphenylglycol
-
Dexamethasone
-
Thyrotropin
-
Thyroxine
-
Hydrocortisone