We observed an interstitial cell tumor in an 18-mo-old captive eland bull (Taurotragus oryx) in Tel Aviv, Israel. The histological description of the tumor in the eland was similar to that described in cattle; however, the appearance of a moderate amount of lipid vacuoles in the cytoplasm of the neoplastic cells was uncharacteristic for bovine interstitial cell tumors. The eland also had clinical signs of gynecomastia.