Abstract
Plasma, tear fluid and swabs from eye, nose and pharynx of 33 patients were examined for presence of hepatitis C virus (HCV) RNA by polymerase chain reaction (PCR). All samples from plasma, tear fluid and eyeswabs were found to show a positive reaction in HCV-RNA PCR. Remarkably, we regularly found greater amounts of amplification products in tear fluid and eyeswabs compared to plasma using the same conditions for sample preparation.
MeSH terms
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Base Sequence
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Blood / microbiology*
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Body Fluids / microbiology
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DNA Primers / genetics
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DNA Probes / genetics
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Eye / microbiology
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Hepacivirus / genetics
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Hepacivirus / isolation & purification*
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Hepatitis C / microbiology
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Humans
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Molecular Sequence Data
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Nose / microbiology
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Pharynx / microbiology
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RNA, Viral / genetics
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RNA, Viral / isolation & purification*
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Tears / microbiology*
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Tissue Distribution
Substances
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DNA Primers
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DNA Probes
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RNA, Viral