Head and neck rhabdomyosarcomas in children: value of clinical and CT findings in the detection of loco-regional relapses

Clin Radiol. 1994 Jun;49(6):412-5. doi: 10.1016/s0009-9260(05)81828-8.

Abstract

Between 1984 and 1990, 16 children who had been treated for a histologically proven head and neck rhabdomyosarcoma developed 19 local recurrences. Fourteen relapses discovered in 11 children (group 1) were based on clinical data acquired 3 to 52 months after completion of treatment. Clinical symptoms (12 patients) or examination (2 patients) led to suspicion of a relapse. The clinical presentation of relapses and that of primary tumour were identical in eight cases. CT scans performed prior to recurrence revealed a stable 'post-therapeutic residue' without mass effect at the original site (12 patients) or was normal (2 patients). Six of these 11 children died at 1 to 15 months and five are alive 12 to 36 months after treatment of recurrence. Five relapses were discovered on CT studies 3 to 15 months after completion of treatment in the remaining five children (group 2). Clinical examination was normal in all cases. CT scans performed 3 months before recurrence showed a stable 'post-therapeutic residue' (4 patients) or was normal (1 patient). All of these five children died 3 to 23 months after the relapse.

MeSH terms

  • Adolescent
  • Brain Neoplasms / diagnostic imaging
  • Child
  • Child, Preschool
  • Female
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / diagnostic imaging*
  • Head and Neck Neoplasms / therapy
  • Humans
  • Infant
  • Male
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / diagnostic imaging*
  • Retrospective Studies
  • Rhabdomyosarcoma / diagnosis
  • Rhabdomyosarcoma / diagnostic imaging*
  • Rhabdomyosarcoma / therapy
  • Tomography, X-Ray Computed*