Abstract
Clonal dissemination of two different MRSA strains, both clumping factor negative, has been observed in Germany for more than a year. Both strains possess the mec-A determinant and each exhibits a characteristic genomic DNA fragment pattern. One strain has spread in the north, the other in the south-west of Germany. Intensive care units are mainly affected by MRSA-infections and probably play a special role in further intra- and inter-hospital spread.
MeSH terms
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Bacteriophage Typing
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Base Sequence
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Coagulase / biosynthesis
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Cross Infection / epidemiology
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Cross Infection / microbiology*
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DNA Primers / chemistry
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DNA, Bacterial / analysis
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DNA, Bacterial / chemistry
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Germany / epidemiology
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Humans
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Intensive Care Units
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Methicillin Resistance* / genetics
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Molecular Sequence Data
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Phenotype
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Polymerase Chain Reaction
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology*
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Staphylococcus Phages
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Staphylococcus aureus / classification*
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Staphylococcus aureus / drug effects
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Staphylococcus aureus / genetics
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Staphylococcus aureus / pathogenicity
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Virulence
Substances
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Coagulase
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DNA Primers
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DNA, Bacterial