Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia

T Sakamoto; H Kaneshige; A Takeshi; T Tsushima; S Hasegawa

doi:10.1378/chest.106.3.965

Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia

Chest. 1994 Sep;106(3):965-7. doi: 10.1378/chest.106.3.965.

Authors

T Sakamoto¹, H Kaneshige, A Takeshi, T Tsushima, S Hasegawa

Affiliation

¹ Division of Pulmonary Medicine, University of Tsukuba, Ibaraki, Japan.

PMID: 8082393
DOI: 10.1378/chest.106.3.965

Abstract

Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.

Publication types

Case Reports
Comparative Study
Review

MeSH terms

Female
Humans
Hypoglycemia / blood
Hypoglycemia / etiology*
Insulin-Like Growth Factor II / analysis*
Mesothelioma / blood
Mesothelioma / complications*
Mesothelioma / surgery
Middle Aged
Molecular Weight
Pleural Neoplasms / blood
Pleural Neoplasms / complications*
Pleural Neoplasms / surgery
Recurrence

Substances

Insulin-Like Growth Factor II