Localization of the gene for ATP citrate lyase (ACLY) distal to gastrin(GAS) and proximal to D17S856 on chromosome 17q12-q21

Genomics. 1994 May 15;21(2):444-6. doi: 10.1006/geno.1994.1293.

Abstract

The gene encoding ATP-citrate lyase, designated ACLY, was mapped to human chromosome 17q12-q21 by PCR on a panel of human/rodent somatic cell hybrids and localized to 17q21.1 by PCR on a panel of radiation hybrids. The radiation hybrid panel indicates that the most likely position of ACLY on 17q21.1 is between gastrin (GAS) and D17S856 at a distance of 170-290 kb from the GAS locus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • ATP Citrate (pro-S)-Lyase / genetics*
  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 17*
  • DNA Primers
  • Gastrins / genetics*
  • Genetic Markers
  • Humans
  • Hybrid Cells
  • Molecular Sequence Data
  • Polymerase Chain Reaction / methods
  • Rats

Substances

  • DNA Primers
  • Gastrins
  • Genetic Markers
  • ATP Citrate (pro-S)-Lyase