Bladder tumor staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging, and late gadolinium-enhanced imaging

Radiology. 1994 Oct;193(1):239-45. doi: 10.1148/radiology.193.1.8090898.

Abstract

Purpose: To evaluate the accuracy of contrast material-enhanced computed tomography (CT), unenhanced T1- and T2-weighted magnetic resonance (MR) imaging, and dynamic gadolinium-enhanced spoiled gradient-echo MR imaging in the staging of bladder cancer.

Materials and methods: Thirty-six patients with histologically proved bladder cancer were prospectively examined with CT and MR imaging before tumor resection. Images were evaluated in a blinded fashion.

Results: All methods depicted tumors comparably well. Staging was correct in 16 of 29 patients (55%) with CT and 27 of 36 patients (75%) overall with MR imaging. Overstaging was the most common error, and both CT and MR imaging were more accurate for higher-staged tumors.

Conclusion: CT and MR imaging perform well in the detection of tumors but are less accurate in staging. Dynamic gadolinium-enhanced MR imaging is better than other techniques, but the difference is not statistically significant.

Publication types

  • Comparative Study

MeSH terms

  • Carcinoma, Transitional Cell / diagnostic imaging
  • Carcinoma, Transitional Cell / epidemiology
  • Carcinoma, Transitional Cell / pathology*
  • Contrast Media
  • Drug Combinations
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Meglumine
  • Middle Aged
  • Neoplasm Staging
  • Organometallic Compounds
  • Pentetic Acid / analogs & derivatives
  • Predictive Value of Tests
  • Prospective Studies
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*
  • Urinary Bladder / diagnostic imaging
  • Urinary Bladder / pathology*
  • Urinary Bladder Neoplasms / diagnostic imaging
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / pathology*

Substances

  • Contrast Media
  • Drug Combinations
  • Organometallic Compounds
  • Meglumine
  • Pentetic Acid
  • Gadolinium DTPA