A frequent EcoRI polymorphism in the bcl-2 gene

P Ghia; I Dianzani; A Serra; C Rosso; F Caligaris-Cappio

doi:10.1007/BF00217784

A frequent EcoRI polymorphism in the bcl-2 gene

Hum Genet. 1993 Jun;91(5):513. doi: 10.1007/BF00217784.

Authors

P Ghia¹, I Dianzani, A Serra, C Rosso, F Caligaris-Cappio

Affiliation

¹ Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italy.

PMID: 8100213
DOI: 10.1007/BF00217784

Abstract

The frequency and Mendelian inheritance of an EcoRI polymorphism mapping within the bcl-2 locus was evaluated. The high frequency of the two identified alleles makes it a useful marker for genes located on the 18q21 region.

MeSH terms

Alleles
Chromosomes, Human, Pair 14*
Chromosomes, Human, Pair 18*
Deoxyribonuclease EcoRI
Humans
Lymphoma, B-Cell / genetics*
Polymorphism, Restriction Fragment Length*
Translocation, Genetic

Substances

Deoxyribonuclease EcoRI