Pretranslational induction of CYP4A subfamily gene products in diabetic rats and reversal by oral vanadate treatment

Drug Metab Dispos. 1993 Jul-Aug;21(4):745-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Oral
  • Animals
  • Blotting, Northern
  • Blotting, Western
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / genetics*
  • Diabetes Mellitus, Experimental / metabolism*
  • Enzyme Induction / drug effects
  • Insulin / pharmacology
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology
  • Multigene Family
  • Protein Biosynthesis
  • RNA, Messenger / metabolism
  • Rats
  • Vanadates / administration & dosage
  • Vanadates / pharmacology*

Substances

  • Insulin
  • RNA, Messenger
  • Vanadates
  • Cytochrome P-450 Enzyme System