Is Cremophor EL, solvent for paclitaxel, cytotoxic?

Lancet. 1993 Oct 2;342(8875):873. doi: 10.1016/0140-6736(93)92735-c.
No abstract available

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Breast Neoplasms / drug therapy
  • Dose-Response Relationship, Drug
  • Doxorubicin / therapeutic use
  • Drug Resistance
  • Glycerol / analogs & derivatives*
  • Glycerol / pharmacology
  • Humans
  • Paclitaxel / pharmacology*
  • Solvents / pharmacology*
  • Tumor Cells, Cultured / drug effects*

Substances

  • Solvents
  • cremophor EL
  • Doxorubicin
  • Paclitaxel
  • Glycerol