The results of two conservative treatment regimens in patients with inoperable brain tumours are presented. The group of 25 patients were treated with protracted telegammatherapy and concomitant multi-drug chemotherapy. Another group of 29 patients were irradiated with shorter series of increasing daily doses, receiving no chemotherapy. There was no statistical difference between survival curves of both groups of patients. The results indicate that irradiation with shorter series causes effects similar to protracted irradiation and allows reduction of treatment time by half.