Abstract
The past year has been marked by the discovery that the influenza virus NS1 protein belongs to the group of viral proteins that regulate the nuclear export of mRNA. This protein, like other viral proteins in this group, such as the Rev protein of human immunodeficiency virus 1 (HIV-1) and the complex of two adenovirus early proteins, has the potential to provide insights into the poorly understood process of the nuclear export of mRNA.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Adenoviridae / genetics
-
Adenoviridae / metabolism
-
Animals
-
Biological Transport
-
Cell Nucleus / metabolism*
-
Cytoplasm / metabolism*
-
Gene Products, rev / physiology
-
HIV-1 / genetics
-
HIV-1 / metabolism
-
Nuclear Envelope / metabolism
-
Orthomyxoviridae / genetics
-
Orthomyxoviridae / metabolism
-
RNA Precursors / metabolism
-
RNA Processing, Post-Transcriptional*
-
RNA, Messenger / metabolism*
-
RNA, Viral / metabolism*
-
Viral Nonstructural Proteins / physiology
-
Viral Proteins / metabolism*
-
rev Gene Products, Human Immunodeficiency Virus
Substances
-
Gene Products, rev
-
INS1 protein, influenza virus
-
RNA Precursors
-
RNA, Messenger
-
RNA, Viral
-
Viral Nonstructural Proteins
-
Viral Proteins
-
rev Gene Products, Human Immunodeficiency Virus