[The effect of exogenous gangliosides on the formation in rats of instrumental movements with tactile control]

Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Nov-Dec;43(6):1129-36.
[Article in Russian]

Abstract

The process of learning and memorization of instrumental reaching movements with pressure on an operandum by a preferable forepaw were studied in white rats after ganglioside injections. The coursed of learning in control and ganglioside injected animals were shown to be alike while some ganglioside treated rats demonstrated increased motor activity. After a 5-week interval animals of both groups were able to perform quick reaching movements, but the storage of ability to push the operandum during the defined time was revealed only in ganglioside injected group. It may be considered that the ganglioside injections support the long-term storage of learned movements with tactile control.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Conditioning, Operant / drug effects*
  • Conditioning, Operant / physiology
  • Feeding Behavior / drug effects
  • Feeding Behavior / physiology
  • Functional Laterality / drug effects
  • Functional Laterality / physiology
  • Gangliosides / pharmacology*
  • Male
  • Motor Activity / drug effects*
  • Motor Activity / physiology
  • Rats
  • Time Factors
  • Touch / drug effects*
  • Touch / physiology

Substances

  • Gangliosides