Inhibition of lipoperoxidation of linoleic acid by five antioxidants of different lipophilicity

Pharmazie. 1994 Jan;49(1):49-52.

Abstract

The efficacy of oxidation inhibition of five natural and synthetic antioxidants (BHT, BHA, nordihydroguaiaretic acid (NDGA), quercetin and rutin) was studied in O/W emulsions. Linoleic acid was used as a reference molecule; the reaction was initiated by an azo-compound. The kAH characterizing the reaction of the antioxidant with the peroxyl radical decreases in the following order: kAH(BHA) > kAH(BHT) > kAH(NDGA) > kAH(quercetin) > kAH(rutin).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry*
  • Azo Compounds / chemistry
  • Chemical Phenomena
  • Chemistry, Physical
  • Chromatography, High Pressure Liquid
  • Emulsions
  • Linoleic Acid
  • Linoleic Acids / chemistry*
  • Lipid Peroxidation*
  • Lipids / chemistry
  • Micelles
  • Oxygen / chemistry
  • Particle Size
  • Solubility
  • Spectrophotometry, Ultraviolet
  • Temperature
  • Viscosity

Substances

  • Antioxidants
  • Azo Compounds
  • Emulsions
  • Linoleic Acids
  • Lipids
  • Micelles
  • Linoleic Acid
  • Oxygen