Abstract
Platelet concentrates (PC) were stored for 6 days in either polyolefin (PO) or polyvinylchloride/di-(2-ethylhexyl)phtalate (PVC/DEHP) bags in 100% plasma or in a synthetic medium with 35 or 10% plasma. For all conditions studied the usual in vitro parameters were well maintained, with a pH above 6.8. In both bag types platelets can be satisfactorily stored for 6 days in a synthetic medium with minimal amounts of residual plasma. For this medium, the PO bag offers a slight advantage with respect to the preservation of platelet ATP content (> 80 versus > 70% in the PVC bags) and aggregation and adhesion capacity. The adhesion capacity increased in the PO bags, while it decreased in the PVC bags.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Acrylates*
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Adenine Nucleotides / blood
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Antigens, CD / analysis
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Antigens, Human Platelet / analysis
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Biomarkers / blood
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Blood Platelets* / chemistry
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Blood Platelets* / physiology
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Blood Platelets* / ultrastructure
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Blood Preservation / instrumentation*
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Diethylhexyl Phthalate
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Energy Metabolism
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Humans
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Plasma
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Platelet Activation
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Platelet Adhesiveness
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Platelet Aggregation
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Polyenes*
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Polyethylenes*
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Polypropylenes*
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Solutions
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Time Factors
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Vinyl Chloride
Substances
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Acrylates
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Adenine Nucleotides
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Antigens, CD
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Antigens, Human Platelet
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Biomarkers
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Polyenes
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Polyethylenes
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Polypropylenes
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Solutions
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PL 732
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Diethylhexyl Phthalate
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Vinyl Chloride