Questionnaire data were collected from 64 direct-care staff members in a residential facility for people with multiple disabilities. Path analyses identified a number of organizational factors that predicted levels of perceived stress, overall job satisfaction, overall life satisfaction, and perceived likelihood of leaving the organization. Factors found to be common influences on all outcome measures included support from other staff (largely supervisory), job variety, staff perceptions of organizational democracy, goodness-of-fit between the attitudes and aims of staff and those of the organization, staff development, and income. Implications of the findings for service managers were discussed.