Spontaneous splenic rupture as the initial manifestation of acute lymphoblastic leukaemia: immunophenotype and cytogenetics

A Altès; S Brunet; C Martinez; J Soler; R Ayats; A Sureda; R López; A Domingo

doi:10.1007/BF01727419

Spontaneous splenic rupture as the initial manifestation of acute lymphoblastic leukaemia: immunophenotype and cytogenetics

Ann Hematol. 1994 Mar;68(3):143-4. doi: 10.1007/BF01727419.

Authors

A Altès¹, S Brunet, C Martinez, J Soler, R Ayats, A Sureda, R López, A Domingo

Affiliation

¹ Department d'Hematologia, Hospital de Sant Pau, Barcelona, Spain.

PMID: 8167180
DOI: 10.1007/BF01727419

Abstract

Spontaneous splenic rupture is a rare, though life-threatening complication of some hematological malignancies and is even more infrequent as the initial symptom of acute lymphoblastic leukemia. We describe the fourth case, to our knowledge, of acute lymphoblastic leukemia presenting as splenic rupture, and for the first time the immunophenotype and cytogenetic pattern observed.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Bone Marrow / immunology
Cytogenetics*
Female
Humans
Immunophenotyping*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology
Rupture, Spontaneous
Splenectomy
Splenic Diseases / etiology*